TY - JOUR
T1 - Bioactive peptides from collagen hydrolysates from squid (Dosidicus gigas) by-products fractionated by ultrafiltration
T2 - Squid-by-products bioactive collagen fractions
AU - Suárez-Jiménez, G. Miroslava
AU - Burgos-Hernández, Armando
AU - Torres-Arreola, Wilfrido
AU - López-Saiz, Carmen M.
AU - Velázquez Contreras, Carlos A.
AU - Ezquerra-Brauer, J. Marina
N1 - Publisher Copyright:
© 2018 Institute of Food Science and Technology
PY - 2019/4/1
Y1 - 2019/4/1
N2 - The bioactive properties of peptide fractions obtained from the hydrolysis of squid (Dosidicus gigas) by-products collagen, using Protease type XIV and ultrafiltration (UFI), were studied. The basic objective was to improve the bioactivity of squid hydrolysates via the application of UFI. Peptide fractions obtained after UFI had higher antioxidant and antimutagenic activities, but the antiproliferative activity did not improve after UFI. Peptides<5 kDa (Fraction F3) showed higher antioxidant and antimutagenic activities, as well as lower antioxidant and antiproliferative activities than both, peptides>10 kDa (F1)and those within the range of>5to<10 kDa (F2). Band at lower field observed in FT-IR spectra and proton-peaks observed at higher1H-NMR fields, both associated to aromatic amino acids, as well as toother antioxidant amino acids such as hydroxyproline, glycine, arginine and lysine, may explain F3 bioactivity. Ultrafiltration can, therefore, be used to improve some bioactivities of squid collagen hydrolysates
AB - The bioactive properties of peptide fractions obtained from the hydrolysis of squid (Dosidicus gigas) by-products collagen, using Protease type XIV and ultrafiltration (UFI), were studied. The basic objective was to improve the bioactivity of squid hydrolysates via the application of UFI. Peptide fractions obtained after UFI had higher antioxidant and antimutagenic activities, but the antiproliferative activity did not improve after UFI. Peptides<5 kDa (Fraction F3) showed higher antioxidant and antimutagenic activities, as well as lower antioxidant and antiproliferative activities than both, peptides>10 kDa (F1)and those within the range of>5to<10 kDa (F2). Band at lower field observed in FT-IR spectra and proton-peaks observed at higher1H-NMR fields, both associated to aromatic amino acids, as well as toother antioxidant amino acids such as hydroxyproline, glycine, arginine and lysine, may explain F3 bioactivity. Ultrafiltration can, therefore, be used to improve some bioactivities of squid collagen hydrolysates
KW - Antimutagenic
KW - antioxidant
KW - bioactive peptides
KW - by-products
KW - squid hydrolysates
KW - ultrafiltration
UR - http://www.scopus.com/inward/record.url?scp=85054584656&partnerID=8YFLogxK
U2 - 10.1111/ijfs.13984
DO - 10.1111/ijfs.13984
M3 - Artículo
AN - SCOPUS:85054584656
SN - 0950-5423
VL - 54
SP - 1054
EP - 1061
JO - International Journal of Food Science and Technology
JF - International Journal of Food Science and Technology
IS - 4
ER -