Abstract

The bioactive properties of peptide fractions obtained from the hydrolysis of squid (Dosidicus gigas) by-products collagen, using Protease type XIV and ultrafiltration (UFI), were studied. The basic objective was to improve the bioactivity of squid hydrolysates via the application of UFI. Peptide fractions obtained after UFI had higher antioxidant and antimutagenic activities, but the antiproliferative activity did not improve after UFI. Peptides<5 kDa (Fraction F3) showed higher antioxidant and antimutagenic activities, as well as lower antioxidant and antiproliferative activities than both, peptides>10 kDa (F1)and those within the range of>5to<10 kDa (F2). Band at lower field observed in FT-IR spectra and proton-peaks observed at higher1H-NMR fields, both associated to aromatic amino acids, as well as toother antioxidant amino acids such as hydroxyproline, glycine, arginine and lysine, may explain F3 bioactivity. Ultrafiltration can, therefore, be used to improve some bioactivities of squid collagen hydrolysates
Original languageEnglish
Pages (from-to)1
Number of pages8
JournalInternational Journal of Food Science and Technology
Volume54
Issue number4
DOIs
StateAccepted/In press - 7 Oct 2018

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Dosidicus gigas
Decapodiformes
Ultrafiltration
ultrafiltration
squid
hydrolysates
Collagen
byproducts
Peptides
Byproducts
collagen
peptides
Bioactivity
Amino acids
Antioxidants
Hydroxyproline
antimutagenic activity
Aromatic Amino Acids
Pronase
Arginine

Keywords

  • Antimutagenic
  • antioxidant
  • bioactive peptides
  • by-products
  • squid hydrolysates
  • ultrafiltration

Cite this

@article{65c4d979ff654eb2b086beae3184d06a,
title = "Bioactive peptides from collagen hydrolysates from squid (Dosidicus gigas) by-products fractionated by ultrafiltration: Squid-by-products bioactive collagen fractions",
abstract = "The bioactive properties of peptide fractions obtained from the hydrolysis of squid (Dosidicus gigas) by-products collagen, using Protease type XIV and ultrafiltration (UFI), were studied. The basic objective was to improve the bioactivity of squid hydrolysates via the application of UFI. Peptide fractions obtained after UFI had higher antioxidant and antimutagenic activities, but the antiproliferative activity did not improve after UFI. Peptides<5 kDa (Fraction F3) showed higher antioxidant and antimutagenic activities, as well as lower antioxidant and antiproliferative activities than both, peptides>10 kDa (F1)and those within the range of>5to<10 kDa (F2). Band at lower field observed in FT-IR spectra and proton-peaks observed at higher1H-NMR fields, both associated to aromatic amino acids, as well as toother antioxidant amino acids such as hydroxyproline, glycine, arginine and lysine, may explain F3 bioactivity. Ultrafiltration can, therefore, be used to improve some bioactivities of squid collagen hydrolysates",
keywords = "Antimutagenic, antioxidant, bioactive peptides, by-products, squid hydrolysates, ultrafiltration",
author = "Su{\'a}rez-Jim{\'e}nez, {G. Miroslava} and Armando Burgos-Hern{\'a}ndez and Wilfrido Torres-Arreola and L{\'o}pez-Saiz, {Carmen M.} and {Vel{\'a}zquez Contreras}, {Carlos A.} and Ezquerra-Brauer, {J. Marina}",
year = "2018",
month = "10",
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doi = "10.1111/ijfs.13984",
language = "Ingl{\'e}s",
volume = "54",
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journal = "International Journal of Food Science and Technology",
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TY - JOUR

T1 - Bioactive peptides from collagen hydrolysates from squid (Dosidicus gigas) by-products fractionated by ultrafiltration

T2 - Squid-by-products bioactive collagen fractions

AU - Suárez-Jiménez, G. Miroslava

AU - Burgos-Hernández, Armando

AU - Torres-Arreola, Wilfrido

AU - López-Saiz, Carmen M.

AU - Velázquez Contreras, Carlos A.

AU - Ezquerra-Brauer, J. Marina

PY - 2018/10/7

Y1 - 2018/10/7

N2 - The bioactive properties of peptide fractions obtained from the hydrolysis of squid (Dosidicus gigas) by-products collagen, using Protease type XIV and ultrafiltration (UFI), were studied. The basic objective was to improve the bioactivity of squid hydrolysates via the application of UFI. Peptide fractions obtained after UFI had higher antioxidant and antimutagenic activities, but the antiproliferative activity did not improve after UFI. Peptides<5 kDa (Fraction F3) showed higher antioxidant and antimutagenic activities, as well as lower antioxidant and antiproliferative activities than both, peptides>10 kDa (F1)and those within the range of>5to<10 kDa (F2). Band at lower field observed in FT-IR spectra and proton-peaks observed at higher1H-NMR fields, both associated to aromatic amino acids, as well as toother antioxidant amino acids such as hydroxyproline, glycine, arginine and lysine, may explain F3 bioactivity. Ultrafiltration can, therefore, be used to improve some bioactivities of squid collagen hydrolysates

AB - The bioactive properties of peptide fractions obtained from the hydrolysis of squid (Dosidicus gigas) by-products collagen, using Protease type XIV and ultrafiltration (UFI), were studied. The basic objective was to improve the bioactivity of squid hydrolysates via the application of UFI. Peptide fractions obtained after UFI had higher antioxidant and antimutagenic activities, but the antiproliferative activity did not improve after UFI. Peptides<5 kDa (Fraction F3) showed higher antioxidant and antimutagenic activities, as well as lower antioxidant and antiproliferative activities than both, peptides>10 kDa (F1)and those within the range of>5to<10 kDa (F2). Band at lower field observed in FT-IR spectra and proton-peaks observed at higher1H-NMR fields, both associated to aromatic amino acids, as well as toother antioxidant amino acids such as hydroxyproline, glycine, arginine and lysine, may explain F3 bioactivity. Ultrafiltration can, therefore, be used to improve some bioactivities of squid collagen hydrolysates

KW - Antimutagenic

KW - antioxidant

KW - bioactive peptides

KW - by-products

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KW - ultrafiltration

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