Biopolymeric Electrospun Nanofibers forWound Dressings in Diabetic Patients

Paola I. Campa-Siqueiros*, Maria M. Castillo-Ortega, Jaime López-Cervantes, Jesús Fernando Ayala-Zavala, David Servin de la Mora-López, Tomas J. Madera-Santana*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Skin wounds are one of the most common afflictions worldwide, caused by laceration or as a consequence of different diseases, such as diabetes. This disease represents around 2.1 trillion dollars in expenses to the global health sector. Diabetic patients have a compromised wound healing process, coupled with a high possibility of infection upon a skin wound. A solution is developing wound dressings with new technologies to obtain new and more efficient materials to deal with this problem. With breakthroughs in nanotechnology, certain materials, such as nanofibers, have been proposed to function as active wound dressings. Morphologically similar to the extracellular matrix, nanofibers are among the most promising candidates to renovate the concept ofwound dressings due to their unique property of high volumesurface area ratio. Electrospinning is a process that can use a broad spectrum of polymers to produce nanofibers. Nevertheless, to help the environment, many assayed proposals for these wound dressings are manufactured from polymers, either natural or synthetic. A collection of studies concerning the use of biopolymeric electrospun nanofibers for wound dressings is reviewed in the present contribution.

Original languageEnglish
Title of host publicationElectrospun Nanofibers
Subtitle of host publicationPrinciples, Technology and Novel Applications
PublisherSpringer International Publishing
Pages207-249
Number of pages43
ISBN (Electronic)9783030999582
ISBN (Print)9783030999575
DOIs
StatePublished - 1 Jan 2022

Bibliographical note

Publisher Copyright:
© The Author(s), under exclusive license to Springer Nature Switzerland AG 2022.

Keywords

  • Biopolymer
  • Chitosan
  • Diabetes
  • Electrospinning
  • Wound dressing

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