Characterization of bone cements prepared with either hydroxyapatite, α-TCP or bovine bone

R. F. Vargas-Coronado, L. H. Chan-Chan, J. M. Cervantes-Uc, J. V. Cauich-Rodríguez, M. C. Piña Barba

Research output: Contribution to journalArticlepeer-review


In this work, we report the preparation of bone cements by using methyl methacrylate (MMA) as a base monomer and either hydroxyapatite (HA), alpha tricalcium phosphate (α-TCP) or bovine bone particles as bioactive fillers. In general, it was observed that curing times increased by the addition of any of these fillers (from 4 to 6.7 min). Maximum temperatures decrease slightly by the addition of 20 wt.% of either α-TCP or bovine bone (80.3°C and 73.2°C respectively) but it did not change by the addition of HA (84.3°C) with respect to PMMA only bone cement used as control. Residual monomer content was lower than 4% in the bioactive bone cements. By using α-TCP or bovine bone compressive strength increased with respect to the unfilled bone cement but it was reduced when HA was used. However, all these formulations fulfill the 70 MPa required for bone cement use. Flexural strength was increased by using either α- TCP o bovine bone but the addition of HA decreased this properties compared to the base bone cement. However, the minimum flexural strength (50 MPa) was fulfilled only in those experimental formulations containing low amounts of α-TCP. The minimum tensile strength (30 MPa) was satisfied by all formulations but it was always lower than the exhibited by the unfilled bone cement.

Original languageEnglish
Pages (from-to)89-96
Number of pages8
JournalRevista Mexicana de Ingenieria Biomedica
Issue number1
StatePublished - Apr 2013


  • Bone cements
  • Bovine bone
  • Hydroxyapatite
  • α-tricalcium phosphate


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