The thermal performance of economical housing located in hot climates remains a pending subject, especially in emerging economies. A cellular concrete mixture was designed, considering its thermophysical properties, to apply the new material into building envelopes. The proposed materials have low density and thermal conductivity to be used as a nonstructural lightweight construction element. From the design stage, a series of wall systems based on cellular concrete was proposed. Whereas in the second phase, the materials were analyzed to obtain the potential energy savings using dynamic simulations. It is foreseen that the energy consumption in buildings located in these climates will continue to increase critically due to the temperature increase associated with climate change. The temperatures predicted mean vote (PMV), electric energy consumption, and CO2 emissions were calculated for three IPCC scenarios. These results will help to identify the impact of climate change on the energy use of the houses built under these weather conditions. The results show that if the conventional concrete blocks continue to be used, the air conditioning energy requirements will increase to 49% for 2030 and 61% by 2050. The proposed cellular concrete could reduce energy consumption between 15% and 28%, and these saving rates would remain in the future. The results indicate that it is necessary to drive the adoption of lightweight materials, so the impact of energy use on climate change can be reduced.