Development of an Electrochemical Sensor Conjugated with Molecularly Imprinted Polymers for the Detection of Enrofloxacin

Amed Gallegos-Tabanico, Jorge Jimenez-Canale, Sergio G. Hernandez-Leon, Alexel J. Burgara-Estrella, Jose Carmelo Encinas-Encinas, Jose A. Sarabia-Sainz*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

An electrochemical sensor was fabricated for the rapid and simple detection of enrofloxacin (EF). Modification of screen-printed gold electrodes (SPE) with molecularly imprinted polymers (MIPs) allowed the detection of enrofloxacin by square wave voltammetry (SWV), measuring the oxidation peak at +0.9 V. The detection principle of molecularly imprinted polymers (MIPs) is based on the formation of binding sites with affinities and specificities comparable with those of natural antibodies. The detection of enrofloxacin showed a linear range of 0.01–0.1 mM with a detection limit LOD of 0.02 mM. The development of a non-imprinted polymer (NIP) control sensor allowed for better and more efficient detection. In addition, the sensor is portable, having the advantage of analyzing and detecting molecules of interest without the need to take the sample to a laboratory.

Original languageEnglish
Article number448
JournalChemosensors
Volume10
Issue number11
DOIs
StatePublished - Nov 2022

Bibliographical note

Publisher Copyright:
© 2022 by the authors.

Keywords

  • SPE
  • electrochemical
  • enrofloxacin
  • molecularly imprinted polymers
  • sensor

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