Dos años de vigilancia de la resistencia a los antibióticos de Escherichia coli uropatógena en una clínica de medicina familiar

Several studies have shown a high prevalence of multidrug resistance to antibiotics in community-acquired uropathogenic Escherichia coli. The prevalence of resistant isolates is variable in different regions, it is important to conduct surveillance studies to select empirical treatment. material and method. We conducted a retrospective study to assess antibiotic resistance in a total 120 isolates of community-acquired uropathogenic Escherichia coli recovered through the years 2013 and 2014 in a first-level care clinic in Hermosillo, Sonora, Mexico. Identification tests, antibiotics susceptibility assays and detection of extended-spectrum β-lactamases (esbl) production were performed using MicroScan (Siemens) system. results. The highest antibiotic resistance rates, were detected to fluoroquinolones (58.3%), trimethoprim-sulfamethoxazole (44.2%) and cephalothin (41.7%). Thirty-five percent of the isolates were esbl producers. In contrast, the lowest resistance rates were observed against nitrofurantoin (3.3%). The most frequent co-resistant phenotype observed was to fluoroquinolones and third-generation cephalosporins (33.3%), followed by fluoroquinolones and trimethoprim-sulfamethoxazole (28.3%). conclusions. A high rate of resistance was detected, except for nitrofurantoin, against antibiotics used for empirical treatment for community-acquired urinary tract infections. The results obtained from this study are cause for epidemiological concern, and a strict follow-up in the coming years is required.