TY - JOUR
T1 - Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico
T2 - PREVISY
AU - Castro-Juarez, Alejandro Arturo
AU - Serna-Gutiérrez, Araceli
AU - Alemán-Mateo, Heliodoro
AU - Gallegos-Aguilar, Ana Cristina
AU - Dórame-López, Norma Alicia
AU - Valenzuela-Sánchez, Abraham
AU - Valenzuela-Guzmán, Diana Marcela
AU - Díaz-Zavala, Rolando Giovanni
AU - Urquidez-Romero, Rene
AU - Esparza-Romero, Julián
N1 - Publisher Copyright:
© 2023 by the authors.
PY - 2023/2
Y1 - 2023/2
N2 - To evaluate the effectiveness of the healthy lifestyle promotion program for Yaquis (PREVISY) on insulin resistance in the short- and medium-term periods in adults who are overweight/obese and have an increased risk for diabetes. Using a translational research design, an intervention program was implemented in a sample of 93 Yaqui adult subjects. The effectiveness of PREVISY was evaluated by comparing the levels of Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) and the Triglycerides-Glucose Index (TyG index) at 6 and 12 months using a paired t-test. Results: In the subjects who completed the program, a decrease in the HOMA-IR index (∆ = −0.91 and ∆ = −1.29, p ≤ 0.05) and the TyG index (∆ = −0.24 y ∆ = −0.20, p ≤ 0.05) was observed in the short- and medium-term period, respectively. Subjects with body weight loss ≥ 10% showed decreased levels of HOMA-IR (∆ = −3.32 and ∆ = −4.89, p ≤ 0.05) and the TyG index (∆ = −0.80 and ∆ = −0.60, p ≤ 0.05) at 6 and 12 months, respectively. A stronger benefit of the program was found in subjects with obesity (vs. overweight) and with high and very high risk of diabetes (vs. moderate risk) in IR markers (p ≤ 0.05). The PREVISY program demonstrated its effectiveness in the improvement of some markers of insulin resistance in Yaqui adults at risk of diabetes.
AB - To evaluate the effectiveness of the healthy lifestyle promotion program for Yaquis (PREVISY) on insulin resistance in the short- and medium-term periods in adults who are overweight/obese and have an increased risk for diabetes. Using a translational research design, an intervention program was implemented in a sample of 93 Yaqui adult subjects. The effectiveness of PREVISY was evaluated by comparing the levels of Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) and the Triglycerides-Glucose Index (TyG index) at 6 and 12 months using a paired t-test. Results: In the subjects who completed the program, a decrease in the HOMA-IR index (∆ = −0.91 and ∆ = −1.29, p ≤ 0.05) and the TyG index (∆ = −0.24 y ∆ = −0.20, p ≤ 0.05) was observed in the short- and medium-term period, respectively. Subjects with body weight loss ≥ 10% showed decreased levels of HOMA-IR (∆ = −3.32 and ∆ = −4.89, p ≤ 0.05) and the TyG index (∆ = −0.80 and ∆ = −0.60, p ≤ 0.05) at 6 and 12 months, respectively. A stronger benefit of the program was found in subjects with obesity (vs. overweight) and with high and very high risk of diabetes (vs. moderate risk) in IR markers (p ≤ 0.05). The PREVISY program demonstrated its effectiveness in the improvement of some markers of insulin resistance in Yaqui adults at risk of diabetes.
KW - Yaqui indigenous
KW - insulin resistance
KW - prevention
KW - type 2 diabetes
UR - http://www.scopus.com/inward/record.url?scp=85147801004&partnerID=8YFLogxK
U2 - 10.3390/nu15030597
DO - 10.3390/nu15030597
M3 - Artículo
C2 - 36771304
AN - SCOPUS:85147801004
SN - 2072-6643
VL - 15
JO - Nutrients
JF - Nutrients
IS - 3
M1 - 597
ER -