Gastrointestinal dysbiosis induced by Nocardia sp. infection in tilapia

Diana Medina-Felix; Francisco Vargas-Albores; Estefanía Garibay-Valdez; Luis Rafael Martínez-Córdova; Marcel Martínez-Porchas

doi:10.1016/j.cbd.2023.101154

Gastrointestinal dysbiosis induced by Nocardia sp. infection in tilapia

Diana Medina-Felix, Francisco Vargas-Albores, Estefanía Garibay-Valdez, Luis Rafael Martínez-Córdova, Marcel Martínez-Porchas^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Nocardiosis has caused high mortalities among fish cultures; however, the effects of Nocardia infections in the fish gastrointestinal microbiota are unknown. In this research, tilapia was infected with Nocardia sp., to analyze the effect of infection on the gastrointestinal microbiota. Tilapia infected with Nocardia sp. reported a 46 % survival (100 % in non-infected). Moreover, the infection caused severe damage to the stomach microbiota, with a loss of diversity and a significant increase of Proteobacteria (94.8 %), resulting in a negative correlation network between Proteobacteria and other important phyla. Nocardia sp. is an emerging pathogen capable of inducing dysbiosis and causing significant mortalities.

Original language	English
Article number	101154
Journal	Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics
Volume	49
DOIs	https://doi.org/10.1016/j.cbd.2023.101154
State	Published - Mar 2024

Bibliographical note

Publisher Copyright:
© 2023 Elsevier Inc.

Keywords

Dysbiosis
Fish disease
Granulomatous disease
Gut microbiota
Nocardiosis

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10.1016/j.cbd.2023.101154

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title = "Gastrointestinal dysbiosis induced by Nocardia sp. infection in tilapia",

abstract = "Nocardiosis has caused high mortalities among fish cultures; however, the effects of Nocardia infections in the fish gastrointestinal microbiota are unknown. In this research, tilapia was infected with Nocardia sp., to analyze the effect of infection on the gastrointestinal microbiota. Tilapia infected with Nocardia sp. reported a 46 % survival (100 % in non-infected). Moreover, the infection caused severe damage to the stomach microbiota, with a loss of diversity and a significant increase of Proteobacteria (94.8 %), resulting in a negative correlation network between Proteobacteria and other important phyla. Nocardia sp. is an emerging pathogen capable of inducing dysbiosis and causing significant mortalities.",

keywords = "Dysbiosis, Fish disease, Granulomatous disease, Gut microbiota, Nocardiosis",

author = "Diana Medina-Felix and Francisco Vargas-Albores and Estefan{\'i}a Garibay-Valdez and Mart{\'i}nez-C{\'o}rdova, {Luis Rafael} and Marcel Mart{\'i}nez-Porchas",

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year = "2024",

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doi = "10.1016/j.cbd.2023.101154",

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volume = "49",

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TY - JOUR

T1 - Gastrointestinal dysbiosis induced by Nocardia sp. infection in tilapia

AU - Medina-Felix, Diana

AU - Vargas-Albores, Francisco

AU - Garibay-Valdez, Estefanía

AU - Martínez-Córdova, Luis Rafael

AU - Martínez-Porchas, Marcel

PY - 2024/3

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N2 - Nocardiosis has caused high mortalities among fish cultures; however, the effects of Nocardia infections in the fish gastrointestinal microbiota are unknown. In this research, tilapia was infected with Nocardia sp., to analyze the effect of infection on the gastrointestinal microbiota. Tilapia infected with Nocardia sp. reported a 46 % survival (100 % in non-infected). Moreover, the infection caused severe damage to the stomach microbiota, with a loss of diversity and a significant increase of Proteobacteria (94.8 %), resulting in a negative correlation network between Proteobacteria and other important phyla. Nocardia sp. is an emerging pathogen capable of inducing dysbiosis and causing significant mortalities.

AB - Nocardiosis has caused high mortalities among fish cultures; however, the effects of Nocardia infections in the fish gastrointestinal microbiota are unknown. In this research, tilapia was infected with Nocardia sp., to analyze the effect of infection on the gastrointestinal microbiota. Tilapia infected with Nocardia sp. reported a 46 % survival (100 % in non-infected). Moreover, the infection caused severe damage to the stomach microbiota, with a loss of diversity and a significant increase of Proteobacteria (94.8 %), resulting in a negative correlation network between Proteobacteria and other important phyla. Nocardia sp. is an emerging pathogen capable of inducing dysbiosis and causing significant mortalities.

KW - Dysbiosis

KW - Fish disease

KW - Granulomatous disease

KW - Gut microbiota

KW - Nocardiosis

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DO - 10.1016/j.cbd.2023.101154

M3 - Artículo

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AN - SCOPUS:85178194388

SN - 1744-117X

VL - 49

JO - Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics

JF - Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics

M1 - 101154

ER -

Gastrointestinal dysbiosis induced by Nocardia sp. infection in tilapia

Abstract

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Keywords

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