Green Synthesis of Zinc Oxide Nanoparticles Using Plant Extracts and Their Antimicrobial Activity

D. C. Bouttier-Figueroa*, M. Cortez-Valadez, M. Flores-Acosta, R. E. Robles-Zepeda*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review


The synthesis of zinc oxide nanoparticles (ZnO NPs) through the use of plant extracts is a remarkably simple, cost-effective, efficient, and environmentally friendly approach. In recent years, there has been a surge in the exploration of eco-friendly methods for synthesizing ZnO NPs, with researchers addressing the potential of extracts derived from various plant components, including leaves, stems, roots, and fruits. This comprehensive review aims to encapsulate and delve into the extensive research surrounding the green synthesis of ZnO NPs, emphasizing their diverse antimicrobial applications while encompassing the latest advancements documented in the literature. Furthermore, this review meticulously examines the sizes and morphological characteristics of the synthesized nanoparticles, offering valuable insights into their structural properties. Finally, a thorough exploration of the potential interaction mechanisms between ZnO NPs and bacterial cell walls was conducted, elucidating how such interactions may induce cell death and highlighting the consequential antimicrobial activity exhibited by these nanoparticles.

Original languageEnglish
StateAccepted/In press - 2024

Bibliographical note

Publisher Copyright:
© The Author(s), under exclusive licence to Springer Science+Business Media, LLC, part of Springer Nature 2024.


  • Antimicrobial activity
  • Green synthesis
  • ZnO nanoparticles


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