Hipoglucemia hiperinsulinémica persistente. Informe de dos casos.

Translated title of the contribution: Persistent hyperinsulinemic hypoglycemia. Two case reports

Norberto Sotelo-Cruz*, Andrés Cordero-Olivares, Carlos Ramírez-Rodríguez, Guillermo López-Cervantes, Jaime Hurtado-Valenzuela, Brenda María López-Cervantes

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


We report two cases of infants who presented seizures and persistent hypoglycemia. In both infants, we established diagnosis of persistent hypoglycemia by hyperinsulinism (PHH); glycemic/insulinic ratio was > 0.3, and we found no pancreatic changes by means of other diagnostic procedures. The medical treatment consisted of hydrocortisone, diazoxide, and octreotide without response. Definitive treatment made was sub-total pancreatectomy; postoperatory evolution was satisfactory, and the histologic report showed changes in Langerhans islet of nesidioblastosis. We conclude that PHH and glucose/insulin ratio > 0.3 indicates that surgical treatment with pancreatectomy should not be delayed.

Translated title of the contributionPersistent hyperinsulinemic hypoglycemia. Two case reports
Original languageSpanish
Pages (from-to)409-414
Number of pages6
JournalCirugia y Cirujanos
Issue number5
StatePublished - 2004
Externally publishedYes


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