In vitro antioxidant, antimutagenic and antiproliferative activities of collagen hydrolysates of jumbo squid ( Dosidicus gigas ) byproducts

Guadalupe Miroslava Suárez-Jiménez, Maribel ROBLES-SÁNCHES Rosario, YÉPIZ-PLASCENCIA Glória, BURGOS-HERNÁNDEZ Armando, Marina EZQUERRA-BRAUER Josafat

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Abstract

Hydrolysates from two different jumbo squid byproducts (fins and arms), produced by trypsin and protease type XIV were compared on the basis of their antioxidant (DPPH and ABTS radical scavenging assays), antimutagenic (Ames test) and antiproliferative (Transformation cell proliferation in M12.C3F6 murine cells) activities. Jumbo squid arms had higher content of collagen than fins, and their hydrolysates had the highest antioxidant activity. Also, jumbo squid arm-derived collagen hydrolyzed with protease XIV showed the highest antimutagenic activity. The four hydrolysates obtained showed low antiproliferative activity, however they are susceptible for further studies to be applied as food additives.
Original languageUndefined/Unknown
JournalCiência e Tecnologia de Alimentos
StatePublished - 2015
Externally publishedYes

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