Microencapsulation of Phenolic Extract from Sea Grape (Coccoloba uvifera L.) with Antimutagenic Activity

Montserrat Calderón-Santoyo, Elda Margarita González-Cruz, Maricarmen Iñiguez-Moreno, Osvaldo Ramos-Martínez, Armando Burgos-Hernández, Juan Arturo Ragazzo-Sánchez*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


This study aimed to microencapsulate the sea grape ethanolic extract by the spray drying process, characterizing the obtained powder, and evaluating its antimutagenicity activity. Microparticles showed a mean size of 6.28 μm and a spherical shape with a smooth surface. The powder had a low moisture content (4.02±0.92 %) and water activity (0.27±0.01), and high solubility (76±3.60 %). Moreover, hygroscopicity (14.75±2.63 g/100 g of powder) and bulk density (0.63±0.03 g/cm3) values suggested that this powder can be easily handled at a pilot or industrial scale. In addition, microencapsulation protected the extract against oxidation by ultraviolet light, improved its thermal stability, and its antimutagenicity activity was similar to fresh sea grape extract. In conclusion, the microencapsulation with maltodextrin by spray drying technique is an alternative to protect bioactive compounds from sea grapes against environmental conditions, maintaining their antimutagenic activity.

Original languageEnglish
Article numbere202200806
JournalChemistry and Biodiversity
Issue number11
StatePublished - Nov 2022

Bibliographical note

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© 2022 Wiley-VHCA AG, Zurich, Switzerland.


  • antimutagenic activity
  • photostability effect
  • sea grape extract
  • spray-drying technique
  • thermal analyses


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