TY - JOUR
T1 - Molecular Characterization of Norovirus Circulating in Northwest Mexico During 2013–2014
AU - Félix-Valenzuela, Leticia
AU - Molina-Chavarria, Alejandro
AU - Enríquez-Hernández, Carmen Itzé
AU - Bolado-Martínez, Enrique
AU - Durazo-Arvizu, María de los Ángeles
AU - Dórame-Castillo, Roberto
AU - Cano-Rangel, Manuel Alberto
AU - Mata-Haro, Verónica
N1 - Publisher Copyright:
© 2020, Springer Science+Business Media, LLC, part of Springer Nature.
PY - 2020/12
Y1 - 2020/12
N2 - Norovirus (NoV) is an important etiological agent of diarrhea in children and adults. In Mexico, NoV screening is not routinely performed. NoV is highly infectious and is responsible for massive outbreaks due to the consumption of contaminated food. The study was a cross-sectional design. Samples of diarrheal stools were collected from (62) children and (38) adults with acute gastroenteritis during 2013–2014. The circulating genogroups of NoV were detected by amplifying the RdRp gene fragment, and for the genotyping, the capsid and polymerase fragments were sequenced. Seventy-seven percent of the analyzed samples were positive for NoV. Genotyping was possible for 51 samples; for polymerase GII.P2, GII.P31, GII.P4, GII.P7, GII.P40, and GI.P14 were identified, whereas for capsid, genotypes GI.3, GII.2, GII.4, GII.5, GII.14, and GII.17. In conclusion, there is a high prevalence of gastroenteritis due to NoV in the northwest of Mexico, including genotypes that have not been reported previously in Mexico.
AB - Norovirus (NoV) is an important etiological agent of diarrhea in children and adults. In Mexico, NoV screening is not routinely performed. NoV is highly infectious and is responsible for massive outbreaks due to the consumption of contaminated food. The study was a cross-sectional design. Samples of diarrheal stools were collected from (62) children and (38) adults with acute gastroenteritis during 2013–2014. The circulating genogroups of NoV were detected by amplifying the RdRp gene fragment, and for the genotyping, the capsid and polymerase fragments were sequenced. Seventy-seven percent of the analyzed samples were positive for NoV. Genotyping was possible for 51 samples; for polymerase GII.P2, GII.P31, GII.P4, GII.P7, GII.P40, and GI.P14 were identified, whereas for capsid, genotypes GI.3, GII.2, GII.4, GII.5, GII.14, and GII.17. In conclusion, there is a high prevalence of gastroenteritis due to NoV in the northwest of Mexico, including genotypes that have not been reported previously in Mexico.
KW - Gastroenteritis
KW - Mexico
KW - Norovirus genotyping
KW - Prevalence
UR - http://www.scopus.com/inward/record.url?scp=85092190115&partnerID=8YFLogxK
U2 - 10.1007/s12560-020-09446-w
DO - 10.1007/s12560-020-09446-w
M3 - Artículo
C2 - 33029763
AN - SCOPUS:85092190115
SN - 1867-0334
VL - 12
SP - 355
EP - 360
JO - Food and Environmental Virology
JF - Food and Environmental Virology
IS - 4
ER -