TY - JOUR
T1 - Nanodiamonds and gold nanoparticles to obtain a hybrid nanostructure with potential applications in biomedicine
AU - Pedroso-Santana, Seidy
AU - Fleitas-Salazar, Noralvis
AU - Sarabia-Sainz, Andrei
AU - Silva-Campa, Erika
AU - Angulo-Molina, Araceli
AU - Pedroza-Montero, Martin
AU - Riera, Raul
PY - 2018/8/24
Y1 - 2018/8/24
N2 - © 2018 IOP Publishing Ltd. Using detonation nanodiamonds and fluorescent nitrogen-vacancy center nanodiamonds, linked to gold nanoparticles, we synthesized two hybrid nanostructures (HGDs) that were subsequently conjugated with a fluorophore. An amplification effect induced by the gold nanoparticles increased the emission spectrum of the fluorophore, maximizing the possibilities for imaging applications of these HGDs. The incubation of the nanostructures with HeLa cells produced no alteration of cell viability after 3 h and showed the presence of nanostructures in the cell cytoplasm at 24 h. These observations also indicate the potential biomedical use of the proposed HGDs.
AB - © 2018 IOP Publishing Ltd. Using detonation nanodiamonds and fluorescent nitrogen-vacancy center nanodiamonds, linked to gold nanoparticles, we synthesized two hybrid nanostructures (HGDs) that were subsequently conjugated with a fluorophore. An amplification effect induced by the gold nanoparticles increased the emission spectrum of the fluorophore, maximizing the possibilities for imaging applications of these HGDs. The incubation of the nanostructures with HeLa cells produced no alteration of cell viability after 3 h and showed the presence of nanostructures in the cell cytoplasm at 24 h. These observations also indicate the potential biomedical use of the proposed HGDs.
U2 - 10.1088/1361-6528/aadad1
DO - 10.1088/1361-6528/aadad1
M3 - Article
C2 - 30113316
JO - Nanotechnology
JF - Nanotechnology
SN - 0957-4484
ER -