Nanodiamonds and gold nanoparticles to obtain a hybrid nanostructure with potential applications in biomedicine

Seidy Pedroso-Santana, Noralvis Fleitas-Salazar, Andrei Sarabia-Sainz, Erika Silva-Campa, Araceli Angulo-Molina, Martin Pedroza-Montero, Raul Riera

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

© 2018 IOP Publishing Ltd. Using detonation nanodiamonds and fluorescent nitrogen-vacancy center nanodiamonds, linked to gold nanoparticles, we synthesized two hybrid nanostructures (HGDs) that were subsequently conjugated with a fluorophore. An amplification effect induced by the gold nanoparticles increased the emission spectrum of the fluorophore, maximizing the possibilities for imaging applications of these HGDs. The incubation of the nanostructures with HeLa cells produced no alteration of cell viability after 3 h and showed the presence of nanostructures in the cell cytoplasm at 24 h. These observations also indicate the potential biomedical use of the proposed HGDs.
Original languageAmerican English
JournalNanotechnology
DOIs
StatePublished - 24 Aug 2018

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