Novel Pectin/Chia-Mucilage Membranes: Human Serum Albumin Adsorption, Biocompatibility, and Physical-Chemical Properties

S. E. Burruel-Ibarra, R. A. Esquer-Osuna, R. G. Valdez-Melchor, D. A. Cuevas-Acuña, L. Quihui Cota, J. Juárez, J. C. Campos-García, E. Valbuena-Gregorio, M. A. López-Mata*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


This study aimed to characterize the physical-chemical and biological properties of pectin (PC)/chia seed mucilage (CM) membranes. PC/CM [100/0 (control), 80/20%, 60/40%, and 40/60% w/w] membranes were prepared using the casting method. The membranes (PC/CM) were thin, yellow, lightly opaque (≈10%) and capable of blocking light UVB (between 66 at 52%). SEM analysis showed the presence of aggregates in the shape of a sphere (≈13 µm) and ovoid (≈25 µm). The proportion of 80/20 showed an increase in tensile strength (29%) and elastic modulus (19%) when compared to the control. FTIR analysis exhibited intermolecular interactions between PCPC, PC-CM, and CM-CM in the membranes. The thermal analysis (600°C) showed a slight improvement in the percentage of residual mass-loss of 3.31% (80/20) that control. The 40/60 membrane showed the lowest percentage of hemolysis (2.94%) but limited human albumin adsorption capacity. These results suggested that the blend PC/CM may be considered as a biomaterial for medical applications.

Original languageEnglish
Pages (from-to)2647-2663
Number of pages17
JournalJournal of Renewable Materials
Issue number6
StatePublished - 2023

Bibliographical note

Funding Information:
Funding Statement: The authors acknowledge the support of the Division of Biological Science and Health of the University of Sonora for the Project USO313006744.

Publisher Copyright:
© 2023, Tech Science Press. All rights reserved.


  • Pectin
  • albumin
  • biomaterial
  • chia mucilage
  • hemolysis
  • membrane


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