TY - JOUR
T1 - Phenolic composition and biological properties of rhus microphylla and myrtillocactus geometrizans fruit extracts
AU - Guía-García, Jorge L.
AU - Charles-Rodríguez, Ana V.
AU - López-Romero, Julio C.
AU - Torres-Moreno, Heriberto
AU - Genisheva, Zlatina
AU - Robledo-Olivo, Armando
AU - Reyes-Valdés, M. Humberto
AU - Ramírez-Godina, Francisca
AU - García-Osuna, Hermila T.
AU - Flores-López, María L.
N1 - Publisher Copyright:
© 2021 by the authors. Licensee MDPI, Basel, Switzerland.
PY - 2021/10
Y1 - 2021/10
N2 - Plants from arid zones of Mexico are an interesting source of phytochemicals that exhibit a large number of biological properties. In this context, Rhus microphylla (Rm) and Myrtillocactus geometrizans (Mg) fruits have been used as folk remedies and to make traditional foods, respectively; however, studies on their composition and bioactivity are limited. Thus, the objective of this work was to evaluate the yields, phenolic composition, and bioactive properties (scavenging and reducing capacities, antiproliferative, and antifungal) of aqueous and hydroalcohol extracts of Rm and Mg fruits obtained by conventional agitation and ohmic heating (OH). The results showed that the Rm fruit extracts had the highest total phenolic content (TPC) values and the strongest scavenging and reducing capacities compared to those of Mg fruits, being characterized by the presence of gallic acid, while the composition of the Mg extracts varied with respect to the extraction conditions used. Regarding antifungal activity in vitro against two phytopathogenic fungi, Rhizopus stolonifer and Fusarium oxysporum, the hydroalcohol extracts obtained by conventional agitation of both plants (RmH-C and MgH-C) showed the best inhibitory effect, respectively. Interestingly, none of the extracts under study presented cytotoxicity against the noncancerous ARPE-19 cell line, while three extracts of Rm fruit exhibited a moderate antiproliferative activity against HeLa (cancerous) cell line. These findings reveal for the first time the potential of Rm and Mg fruits as a new source of bioactive compounds for future industrial applications.
AB - Plants from arid zones of Mexico are an interesting source of phytochemicals that exhibit a large number of biological properties. In this context, Rhus microphylla (Rm) and Myrtillocactus geometrizans (Mg) fruits have been used as folk remedies and to make traditional foods, respectively; however, studies on their composition and bioactivity are limited. Thus, the objective of this work was to evaluate the yields, phenolic composition, and bioactive properties (scavenging and reducing capacities, antiproliferative, and antifungal) of aqueous and hydroalcohol extracts of Rm and Mg fruits obtained by conventional agitation and ohmic heating (OH). The results showed that the Rm fruit extracts had the highest total phenolic content (TPC) values and the strongest scavenging and reducing capacities compared to those of Mg fruits, being characterized by the presence of gallic acid, while the composition of the Mg extracts varied with respect to the extraction conditions used. Regarding antifungal activity in vitro against two phytopathogenic fungi, Rhizopus stolonifer and Fusarium oxysporum, the hydroalcohol extracts obtained by conventional agitation of both plants (RmH-C and MgH-C) showed the best inhibitory effect, respectively. Interestingly, none of the extracts under study presented cytotoxicity against the noncancerous ARPE-19 cell line, while three extracts of Rm fruit exhibited a moderate antiproliferative activity against HeLa (cancerous) cell line. These findings reveal for the first time the potential of Rm and Mg fruits as a new source of bioactive compounds for future industrial applications.
KW - Antifungal activity
KW - Antioxidant activity
KW - Antiproliferative activity
KW - Myrtillocactus geometrizans
KW - Ohmic heating
KW - Phenolic compounds
KW - Rhus microphylla
UR - http://www.scopus.com/inward/record.url?scp=85115810494&partnerID=8YFLogxK
U2 - 10.3390/plants10102010
DO - 10.3390/plants10102010
M3 - Artículo
C2 - 34685819
AN - SCOPUS:85115810494
SN - 2223-7747
VL - 10
JO - Plants
JF - Plants
IS - 10
M1 - 2010
ER -