Potencial antioxidante, antihemólisis y retinoprotectorr de compuestos lipídicos bioactivos provenientes del músculo del camarón salvaje (Litopenaeus stylirostris)

Translated title of the contribution: Antioxidant, antihemolysis, and retinoprotective potentials of bioactive lipidic compounds from wild shrimp (Litopenaeus stylirostris) muscle

Joel Said García-Romo, Luis Noguera-Artiaga, Alma Carolina Gálvez-Iriqui, Martin Samuel Hernández-Zazueta, Daniel Fernando Valenzuela-Cota, Ricardo Iván González-Vega, Maribel Plascencia-Jatomea, María Guadalupe Burboa-Zazueta, Edgar Sandoval-Petris, Rosario Maribel Robles-Sánchez, Josué Juárez, Javier Hernández-Martínez, Hisila del Carmen Santacruz-Ortega, Armando Burgos-Hernández*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Scopus citations

Abstract

The oxidative stress damage on cells is an example of roles in the pathogenesis of different degenerative diseases and the search of compounds that can slow this oxidation is continuous. The aim of this work was to obtain bioactive fractions from wild shrimp (Litopenaeus stylirostris) muscle, in order to evaluate their protective capacity and chemo-structurally characterize them. ABTS and DPPH, and FRAP assays suggested that bioactive fractions possess free radical-scavenging capacity, and reducing power, respectively. An inhibitory effect observed on AAPH-induced hemolysis and results from an H2O2-derived radicals-scavenging assay (retinoprotective) suggest that these fractions can exert their protective activity in human cells. UV–Vis, fluorescence, 13C-, 1H-NMR, and ESI-MS studies performed on the most bioactive fraction, suggests that their main components are eicosapentaenoic acid, dioctyl phthalate, and a possibly novel indolocarbazole alkaloid derivative. These results suggest that these compounds are good candidates to further investigations as possible chemoprotective agents.

Translated title of the contributionAntioxidant, antihemolysis, and retinoprotective potentials of bioactive lipidic compounds from wild shrimp (Litopenaeus stylirostris) muscle
Original languageSpanish
Pages (from-to)153-163
Number of pages11
JournalCYTA - Journal of Food
Volume18
Issue number1
DOIs
StatePublished - 1 Jan 2020

Bibliographical note

Publisher Copyright:
© 2020, © 2020 The Author(s). Published with license by Taylor & Francis Group, LLC.

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