Retino-protective effect of Bucida buceras against oxidative stress induced by H2O2 in human retinal pigment epithelial cells line

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Abstract

Reactive Oxygen Species (ROS) impair the physiological functions of Retinal Pigment Epithelial (RPE)
cells, which are known as one major cause of age-related macular degeneration and retinopathy diseases. The purpose
of this study is to explore the cytoprotective effects of the antioxidant Bucida buceras extract in co-treatment with
hydrogen peroxide (H2O2) delivery as a single addition or with continuous generation using glucose oxidase (GOx) in
ARPE-19 cell cultures. The mechanism of Bucida buceras extract is believed to be associated with their antioxidant
capacity to protect cells against oxidative stress.
Original languageEnglish
Article number254
Pages (from-to)1-22
Number of pages22
JournalBMC Complementary and Alternative Medicine
Volume15
Issue number254
StatePublished - 30 Aug 2015

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