Abstract
Reactive Oxygen Species (ROS) impair the physiological functions of Retinal Pigment Epithelial (RPE)
cells, which are known as one major cause of age-related macular degeneration and retinopathy diseases. The purpose
of this study is to explore the cytoprotective effects of the antioxidant Bucida buceras extract in co-treatment with
hydrogen peroxide (H2O2) delivery as a single addition or with continuous generation using glucose oxidase (GOx) in
ARPE-19 cell cultures. The mechanism of Bucida buceras extract is believed to be associated with their antioxidant
capacity to protect cells against oxidative stress.
cells, which are known as one major cause of age-related macular degeneration and retinopathy diseases. The purpose
of this study is to explore the cytoprotective effects of the antioxidant Bucida buceras extract in co-treatment with
hydrogen peroxide (H2O2) delivery as a single addition or with continuous generation using glucose oxidase (GOx) in
ARPE-19 cell cultures. The mechanism of Bucida buceras extract is believed to be associated with their antioxidant
capacity to protect cells against oxidative stress.
| Original language | English |
|---|---|
| Article number | 254 |
| Pages (from-to) | 1-22 |
| Number of pages | 22 |
| Journal | BMC Complementary and Alternative Medicine |
| Volume | 15 |
| Issue number | 254 |
| State | Published - 30 Aug 2015 |