Risk factors for three-vessel coronary artery disease in patients of Northwest Mexico

Cuitlahuac Arroyo-Rodríguez, Olga Rosa Brito-Zurita, Santiago Sandoval-Navarrete, Rogelio Solis-Vásquez, José Manuel Ornelas-Aguirre*, Celestino Olea-Hernández, César Vásquez-Serna, Amanda Marcela Castelan-Ojeda

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: Three-vessel coronary artery disease is an advanced manifestation of atherosclerosis, with high prevalence in Mexico. Objective: The aim of this study was to describe coronary risk factors in a group of patients with three-vessel coronary artery disease in Northwest Mexico. Methods: A cross sectional study was conducted on a population with three-vessel coronary artery disease from May 2015 to February 2016. The disease was defined when ≥70% stenosis was present in each major epicardial coronary artery. Anthropometric and biochemical parameters were measured in each patient. Ankle-Brachial Index was measured with vascular ultrasound, and Syntax score calculation with an on-line application. Statistical analysis for qualitative differences was performed using Pearson χ2 test, with p < 0.05 being considered as significant. Results: The study included 100 patients, of whom 75 were male (mean age 63 ± 9 years) and 25 female (mean age 69 ± 9 years). The coronary risk factors observed were diabetes (58%), hypertension (86%), smoking (68%), dyslipidaemia (100%), metabolic syndrome (71%), and obe-sity/overweight (75%). Diabetes and metabolic syndrome prevalence was higher in women (p = 0.03), but smoking was higher in men (76%, p = 0.003). Ankle-Brachial Index was abnormal in 58% of patients, the mean Syntax score was in 36.9 ± 11.5, and the prevalence of left main coronary heart disease was 36%. Conclusions: This group of patients with complex coronary lesions has a high prevalence of coronary risk factors, which could represent a worse prognosis.

Translated title of the contributionFactores de riesgo para la enfermedad arterial coronaria de tres vasos en pacientes del Noroeste de México
Original languageEnglish
Pages (from-to)423-431
Number of pages9
JournalArchivos de Cardiologia de Mexico
Volume88
Issue number5
DOIs
StatePublished - Dec 2018

Bibliographical note

Publisher Copyright:
© 2018 Instituto Nacional de Cardiología Ignacio Chávez.

Keywords

  • Ankle-Brachial Index
  • Atherosclerosis
  • Coronary artery disease
  • Mexico
  • Risk factors
  • Syntax score

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