Severe Leptospirosis in a Mexican Woman

Ana Paola Balderrama-Carmona, Daniel Cadena-Orea, Santiago Sánchez-Arteaga, María Luisa Aguilera-Ávila, José Guadalupe Soñanez-Organis, Alan Andreí López-López, Luis Alberto Zamora-Alvarez, Gabriela de Los Ángeles Díaz-Reyes, Norma Patricia Adan-Bante

Research output: Contribution to journalArticlepeer-review


OBJECTIVE: To describe a severe case of infection by Leptospira in a woman in the northwest of Mexico. CASE REPORT: A 55-yearold woman from Sonora, México arrived at the Intensive Care Unit due to severe multiple organ failure primarily affecting the respiratory, renal and hepatic systems. Diagnostic tests were performed, and they were positive for anti-Leptospira antibodies, IgM and IgG; and spirochetes were observed on dark field microscopy and confirmed by Polymerase Chain Reaction (PCR). Doxycycline and platelet apheresis transfusion were used as treatment, which led to a very slow recovery. CONCLUSION: The information presented in this study may help in the identification of pathology caused by spirochetes. This case report is the first to present a case of severe leptospirosis in Sonora, México.

Original languageEnglish
Pages (from-to)67-70
Number of pages4
JournalActa medica academica
Issue number1
StatePublished - 1 Apr 2020

Bibliographical note

Publisher Copyright:
Copyright © 2020 by Academy of Sciences and Arts of Bosnia and Herzegovina.


  • Acute Febrile Illness
  • Borrelia
  • Leptospirosis
  • Renal Failure
  • Vector-Borne Disease


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