Suplementación con salvado de sorgo mejora la dislipidemia, desregulación de glucosa, inflamación y estrés oxidativo inducidos por una dieta alta en grasa en ratas

Translated title of the contribution: Sorghum bran supplementation ameliorates dyslipidemia, glucose dysregulation, inflammation and stress oxidative induced by a high-fat diet in rats

Norma Julieta Salazar-López, Gustavo A. González-Aguilar, Ofelia Rouzaud-Sández, Guadalupe Loarca-Piña, Shela Gorinstein, Maribel Robles-Sánchez*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

A study on the effects of extruded sorghum bran (ESB) or raw sorghum bran (RSB) on biomarkers of glucose dysregulation, dyslipidemia, inflammation, and antioxidant potential induced by a high-fat diet (HFD) in rats was carried out. Four groups of male Wistar rats (six per group) consumed a basal diet (BD), which were supplemented with either lard at 310 g/kg (HFD) or lard and ESB at 180 g/kg (HFD + ESB) or lard and RSB (HFD + RSB), for 8 weeks. The intake of HFD supplemented with ESB or RSB hindered the fat storage in adipocytes of abdominal tissue, dyslipidemia and the loss of glucose homeostasis. A positive correlation between inflammation biomarkers (Interleukin-1β and Interleukin-6) and glucose homeostasis was observed, while a negative correlation between antioxidant capacity (TEAC) and Interleukin-1β and Interleukin-6 was observed. As a conclusion, the ESB or RSB may be intended as part of healthy diets.

Translated title of the contributionSorghum bran supplementation ameliorates dyslipidemia, glucose dysregulation, inflammation and stress oxidative induced by a high-fat diet in rats
Original languageSpanish
Pages (from-to)20-30
Number of pages11
JournalCYTA - Journal of Food
Volume18
Issue number1
DOIs
StatePublished - 1 Jan 2020

Bibliographical note

Publisher Copyright:
© 2019, © 2019 The Author(s). Published with license by Taylor & Francis Group, LLC.

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