The Hexane Fraction of Bursera microphylla A. Gray Induces p21-Mediated Antiproliferative and Proapoptotic Effects in Human Cancer-Derived Cell Lines

Sabrina Adorisio, Alessandra Fierabracci, Giulia Gigliarelli, Isabella Muscari, Lorenza Cannarile, Anna Marina Liberati, Maria Carla Marcotullio, Carlo Riccardi, Massimo Curini, Ramon Enrique Robles Zepeda, Domenico V. Delfino

Research output: Contribution to journalArticlepeer-review

7 Scopus citations
Original languageAmerican English
Pages (from-to)138-147
Number of pages10
JournalIntegrative Cancer Therapies
Volume17
Issue number1
DOIs
StatePublished - 1 Mar 2018

Keywords

  • Bursera microphylla A. Gray
  • Mexican traditional medicine
  • anti-proliferative effect
  • human cancer cell lines
  • p21
  • pro-apoptotic effect
  • Caspase 3/metabolism
  • Jurkat Cells
  • HCT116 Cells
  • Humans
  • Apoptosis/drug effects
  • Tumor Suppressor Protein p53/metabolism
  • Cell Cycle/drug effects
  • Bursera/chemistry
  • MCF-7 Cells
  • U937 Cells
  • K562 Cells
  • Cell Line, Tumor
  • HL-60 Cells
  • Cell Proliferation/drug effects
  • Cyclin-Dependent Kinase Inhibitor p21/metabolism
  • Plant Extracts/pharmacology
  • Hexanes/chemistry

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