The role of ion channels on the physiology of the neurovascular unit and the regulation of cerebral blood flow

Marcelino Montiel-Herrera*, Denisse García-Villa, Guillermo López-Cervantes, Daniel Reyes-Haro, J. Abraham Domínguez-Avila, Gustavo A. González-Aguilar

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

The neurovascular unit, composed of neurons, brain endothelial cells, and glial cells, regulates cerebral blood flow. Physical and chemical signals govern the physiology of the neurovascular unit within this cell network. This manuscript will briefly discuss recent evidence about the contribution of this cell network and its plethora of ion channels, to the leading cellular mechanisms involved in the physiology of the neurovascular unit.

Original languageEnglish
Pages (from-to)1004-1013
Number of pages10
JournalJournal of Cellular Neuroscience and Oxidative Stress
Volume13
Issue number2
DOIs
StatePublished - 2021

Bibliographical note

Funding Information:
Contract grant sponsor: SEP-PRODEP, Contract grant number: Project 511-6/17-7715. :e thank Miriam +erninde-zMorales for her helpful comments on the manuscript and Karla Zavalza-Ortega for technical help. 7he authors thank LCC -essica *onzilez Norris for proofreading the English version of this manuscript.

Publisher Copyright:
© 2021 Suleyman Demirel University. All rights reserved.

Keywords

  • Astrocyte End-feet
  • Capillaries
  • Endothelial Cell
  • Ion Channels
  • Neurovascular
  • Vascular Smooth Muscle Cell

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