Translational study of obesity management using the Diabetes Prevention Program "Group Lifestyle Balance" in primary care clinics and public hospitals from Mexico: Study protocol

Rolando Giovanni Díaz-Zavala*, Brianda Ioanna Armenta-Guirado, Teresita de Jesús Martínez-Contreras, Maria del Carmen Candia-Plata, Julián Esparza-Romero, Raúl Martínez-Mir, Michelle M. Haby, Mauro E. Valencia

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Introduction: Obesity is the main modifiable risk factor for the development of chronic diseases in Mexico. Several randomized controlled trials have shown that intensive lifestyle programs are efficacious for the management of obesity. These programs include frequent sessions (14 or more contacts in the first 6 months) focused on diet and physical activity and use a behavior change protocol. However, most Mexican primary care clinics and public hospitals apply traditional treatments for obesity management with limited results on weight loss. The purpose of the study is to evaluate the effectiveness of the Diabetes Prevention Program (DPP) "Group Lifestyle Balance" for weight loss among adults with overweight and obesity from baseline to 6 months and from baseline to 12 months in primary care clinics and public hospitals from Sonora, Mexico. Material and Methods: This is a translational, multi-center, non-controlled, 6 and 12-month follow-up clinical study with a pre-test and post-test design. Healthcare providers from two primary care clinics, two hospitals and one university clinic will be trained with the DPP protocol to implement on their patients with overweight and obesity. Body weight, body mass index, waist circumference, systolic and diastolic blood pressure, depression, quality of life and stress scales will be measured in participants receiving the program at baseline, 6 and 12 months. Biochemical parameters will be measured at baseline and 12 months. The primary outcome is the change in body weight at 6 and 12 months. Discussion: This study will provide scientific evidence of the effectiveness of the DPP protocol as a model for obesity management in real world clinical practice among the adult Mexican population.

Original languageEnglish
Pages (from-to)369-383
Number of pages15
JournalRevista Espanola de Nutricion Humana y Dietetica
Issue number4
StatePublished - 2017

Bibliographical note

Funding Information:
We thank to the University of Sonora for funding this project. Special thanks to Dr. Ramón Enrique Robles Zepeda (Director, Division of Biological and Health Sciences) and to Dra. Adriana Garibay Escobar (Head, Department of Chemical and Biological Sciences) for their support and resources to implement the study. Special thanks to Rocío Ayala for technical support on writing in English the first version of the manuscript.


  • Attitudes
  • Diabetes prevention program
  • Health knowledge
  • Life style
  • Obesity
  • Practice
  • Translational medical research
  • Weight loss


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