Two cases of hypergranular acute lymphoblastic leukemia

Enrique Bolado-Martínez; Martha Vivanco-Jiménez; Francisco García-Ramírez; Guillermo Ruiz-Reyes; Alejandro Ruiz-Argüelles; Guillermo J. Ruiz-Argüelles

Two cases of hypergranular acute lymphoblastic leukemia

Enrique Bolado-Martínez, Martha Vivanco-Jiménez, Francisco García-Ramírez, Guillermo Ruiz-Reyes, Alejandro Ruiz-Argüelles, Guillermo J. Ruiz-Argüelles^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Two patients with hypergranular acute lymphoblastic leukemia are presented: they represent 1.4% of patients with acute lymphoblastic leukemia studied and treated in a single institution in the past 12 years. This frequency is substantially lower than that reported in Caucasian populations. The blast cells of the patients disclosed an early-B phenotype, displaying CD45, CD10 and CD19 antigens. The cytoplasmic granules were positive for the PAS reaction. Both patients died early after starting treatment; a poor prognosis has been recorded previously for patients with this type of malignancy.

Original language	English
Pages (from-to)	227-230
Number of pages	4
Journal	Revista de Investigacion Clinica
Volume	49
Issue number	3
State	Published - May 1997
Externally published	Yes

Keywords

Acute leukemia
Early B leukemia
Hypergranular leukemia
Leukemia
Lymphoblastic leukemia

Cite this

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title = "Two cases of hypergranular acute lymphoblastic leukemia",

abstract = "Two patients with hypergranular acute lymphoblastic leukemia are presented: they represent 1.4% of patients with acute lymphoblastic leukemia studied and treated in a single institution in the past 12 years. This frequency is substantially lower than that reported in Caucasian populations. The blast cells of the patients disclosed an early-B phenotype, displaying CD45, CD10 and CD19 antigens. The cytoplasmic granules were positive for the PAS reaction. Both patients died early after starting treatment; a poor prognosis has been recorded previously for patients with this type of malignancy.",

keywords = "Acute leukemia, Early B leukemia, Hypergranular leukemia, Leukemia, Lymphoblastic leukemia",

author = "Enrique Bolado-Mart{\'i}nez and Martha Vivanco-Jim{\'e}nez and Francisco Garc{\'i}a-Ram{\'i}rez and Guillermo Ruiz-Reyes and Alejandro Ruiz-Arg{\"u}elles and Ruiz-Arg{\"u}elles, {Guillermo J.}",

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T1 - Two cases of hypergranular acute lymphoblastic leukemia

AU - Bolado-Martínez, Enrique

AU - Vivanco-Jiménez, Martha

AU - García-Ramírez, Francisco

AU - Ruiz-Reyes, Guillermo

AU - Ruiz-Argüelles, Alejandro

AU - Ruiz-Argüelles, Guillermo J.

PY - 1997/5

Y1 - 1997/5

N2 - Two patients with hypergranular acute lymphoblastic leukemia are presented: they represent 1.4% of patients with acute lymphoblastic leukemia studied and treated in a single institution in the past 12 years. This frequency is substantially lower than that reported in Caucasian populations. The blast cells of the patients disclosed an early-B phenotype, displaying CD45, CD10 and CD19 antigens. The cytoplasmic granules were positive for the PAS reaction. Both patients died early after starting treatment; a poor prognosis has been recorded previously for patients with this type of malignancy.

AB - Two patients with hypergranular acute lymphoblastic leukemia are presented: they represent 1.4% of patients with acute lymphoblastic leukemia studied and treated in a single institution in the past 12 years. This frequency is substantially lower than that reported in Caucasian populations. The blast cells of the patients disclosed an early-B phenotype, displaying CD45, CD10 and CD19 antigens. The cytoplasmic granules were positive for the PAS reaction. Both patients died early after starting treatment; a poor prognosis has been recorded previously for patients with this type of malignancy.

KW - Acute leukemia

KW - Early B leukemia

KW - Hypergranular leukemia

KW - Leukemia

KW - Lymphoblastic leukemia

UR - http://www.scopus.com/inward/record.url?scp=3242821561&partnerID=8YFLogxK

M3 - Artículo

SN - 0034-8376

VL - 49

SP - 227

EP - 230

JO - Revista de Investigacion Clinica

JF - Revista de Investigacion Clinica

IS - 3

ER -

Two cases of hypergranular acute lymphoblastic leukemia

Abstract

Keywords

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