Utilization of chitin and chitosan based materials for protease immobilization: Stabilization effects and applications

J. A. Salazar-Leyva, J. Lizardi-Mendoza, J. C. Ramírez-Suarez, G. García-Sánchez, J. M. Ezquerra-Brauer, E. M. Valenzuela-Soto, M. G. Carvallo-Ruiz, M. E. Lugo-Sánchez, R. Pacheco-Aguilar

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

Proteolytic enzymes have a wide range of applications in different industrial fields therefore the development of strategies focused in the optimization of their catalytic performance is a topic of great interest. Enzyme immobilization onto solid supports induces changes at structural level in the immobilized systems, and consequently some reaction characteristics can be enhanced; furthermore, immobilized enzymes can be reused in the same process. Due to the unique physiccochemical and functional properties that chitin and its derivate chitosan possess, these biopolymers are an excellent option as support for enzyme immobilization. This review discusses the effects on the biochemical and operational performance of proteases immobilized in chitin and chitosan based materials. Some aspects related with the industrial applications of the immobilization systems are also mentioned.

Translated title of the contributionUtilización de materiales a base de quitina y quitosano en la inmovilización de proteasas: Efectos en su estabilización y aplicaciones
Original languageEnglish
Pages (from-to)129-150
Number of pages22
JournalRevista Mexicana de Ingeniera Quimica
Volume13
Issue number1
StatePublished - 2014

Keywords

  • Chitin
  • Chitosan
  • Immobilization
  • Proteases
  • Stability

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