A potential inflammatory role of IL-31 in psoriatic arthritis: A correlation with Th17 cytokine profile

L. A. Bautista-Herrera, U. De la Cruz-Mosso, I. V. Román-Fernández, I. Parra-Rojas, J. G. Soñanez-Organis, J. Hernández-Bello, R. A. Morales-Zambrano, G. D. Villanueva-Quintero, J. F. Muñoz-Valle

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

Resumen

The goals of our study were to determine the possible association of interleukin (IL)-31 with Th17 cytokine profile in serum and to quantify retinoic acid-related orphan receptor C (RORC) mRNA expression in psoriatic arthritis (PsA) patients. This cross-sectional study was conducted in 50 patients with PsA and 30 control subjects (CS) matched by age and gender. The cytokine serum levels were quantified by magnetic bead-based assay using the Bio-Plex MAGPIX system, and RORC mRNA expression was determined by quantitative polymerase chain reaction (qPCR). As a result, significant differences in IL-31 were observed between study groups (77.23 pg/mL in PsA vs 64.4 pg/mL in CS, P 
Idioma originalInglés estadounidense
PublicaciónInternational journal of immunopathology and pharmacology
Volumen34
DOI
EstadoPublicada - 1 ene 2020

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