TY - JOUR
T1 - A potential inflammatory role of IL-31 in psoriatic arthritis: A correlation with Th17 cytokine profile
AU - Bautista-Herrera, L. A.
AU - De la Cruz-Mosso, U.
AU - Román-Fernández, I. V.
AU - Parra-Rojas, I.
AU - Soñanez-Organis, J. G.
AU - Hernández-Bello, J.
AU - Morales-Zambrano, R. A.
AU - Villanueva-Quintero, G. D.
AU - Muñoz-Valle, J. F.
PY - 2020/1/1
Y1 - 2020/1/1
N2 - The goals of our study were to determine the possible association of interleukin (IL)-31 with Th17 cytokine profile in serum and to quantify retinoic acid-related orphan receptor C (RORC) mRNA expression in psoriatic arthritis (PsA) patients. This cross-sectional study was conducted in 50 patients with PsA and 30 control subjects (CS) matched by age and gender. The cytokine serum levels were quantified by magnetic bead-based assay using the Bio-Plex MAGPIX system, and RORC mRNA expression was determined by quantitative polymerase chain reaction (qPCR). As a result, significant differences in IL-31 were observed between study groups (77.23 pg/mL in PsA vs 64.4 pg/mL in CS, P
AB - The goals of our study were to determine the possible association of interleukin (IL)-31 with Th17 cytokine profile in serum and to quantify retinoic acid-related orphan receptor C (RORC) mRNA expression in psoriatic arthritis (PsA) patients. This cross-sectional study was conducted in 50 patients with PsA and 30 control subjects (CS) matched by age and gender. The cytokine serum levels were quantified by magnetic bead-based assay using the Bio-Plex MAGPIX system, and RORC mRNA expression was determined by quantitative polymerase chain reaction (qPCR). As a result, significant differences in IL-31 were observed between study groups (77.23 pg/mL in PsA vs 64.4 pg/mL in CS, P
KW - IL-31
KW - RORC
KW - Th17 cytokine profile
KW - mRNA expression
KW - psoriatic arthritis
UR - https://www.mendeley.com/catalogue/207c7530-f727-32ee-875d-fe4b95f64f38/
U2 - 10.1177/2058738420907186
DO - 10.1177/2058738420907186
M3 - Article
C2 - 32138573
SN - 2058-7384
VL - 34
JO - International journal of immunopathology and pharmacology
JF - International journal of immunopathology and pharmacology
ER -