An Updated Overview on the Resistance and Virulence of UPEC: An Updated Overview on the Resistance and Virulence of UPEC

Título traducido de la contribución: Panorama actualizado de la resistencia y virulencia de las UPEC: Panorama actualizado de la resistencia y virulencia de las UPEC

Edwin Barrios-Villa, Luciana Robino Picón, Rodolfo Bernal Reynaga, Margarita M.P. Arenas-Hernández*

*Autor correspondiente de este trabajo

Producción científica: Capítulo del libro/informe/acta de congresoCapítulorevisión exhaustiva

Resumen

Among infections related to ExPEC pathogens, UTIs caused by UPEC are the most prevalent in children and adults worldwide. The latter pathogenic strains exhibit an extensive set of virulence factors such as adhesins, iron uptake systems, and toxins that provide them with the ability to colonize and invade the urinary tract causing different pathologies. Besides these properties, UPEC strains have been reported to possess multidrug resistance to commonly used antibiotics such as β-lactams, fluoroquinolones, carbapenems, and cephalosporins, which complicate the treatment and demonstrate the need of alternative strategies against these pathogens. Updated strategies include vaccines, plant extracts, probiotics, phage therapy, and others, but they need to be widely evaluated before applying them as a common form of therapy. Finally, it is important to note that epidemiological studies that can identify UPEC are necessary to find the most effective way to avoid spread and infection with resistant strains and combat them with novel, high-efficiency treatments.
Título traducido de la contribuciónPanorama actualizado de la resistencia y virulencia de las UPEC: Panorama actualizado de la resistencia y virulencia de las UPEC
Idioma originalInglés estadounidense
Título de la publicación alojadaAn Updated Overview on the Resistance and Virulence of UPEC
Subtítulo de la publicación alojadaAn Updated Overview on the Resistance and Virulence of UPEC
EditoresAlfredo G. Torres
Lugar de publicaciónEstados Unidos
EditorialSpringer Nature
Capítulo11
Páginas249-276
Número de páginas28
ISBN (versión digital)978-3-031-29882-0
ISBN (versión impresa)978-3-031-30394-4, 978-3-031-29881-3
DOI
EstadoPublicada - 29 jun. 2023

Palabras clave

  • E. coli
  • UPEC
  • Resistance
  • Virulence

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