Antibacterial activity of sonoran propolis and some of its constituents against clinically significant vibrio species

Moises Navarro-Navarro, Patricia Ruiz-Bustos, Dora Valencia, Ramón Robles-Zepeda, Eduardo Ruiz-Bustos, Claudia Virués, Javier Hernandez, Zaira Domínguez, Carlos Velazquez*

*Autor correspondiente de este trabajo

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

16 Citas (Scopus)

Resumen

The aim of the present study was to evaluate the anti-Vibrio activity of propolis collected from three different areas of the Sonoran Desert in northwestern, Mexico [Pueblo de Alamos (PAP), Ures (UP), and Caborca (CP)]. The anti-Vibrio spp. activity of Sonoran propolis was determined by the broth microdilution method. UP propolis showed the highest antibacterial activity [minimal inhibitory concentration (MIC50)<50 μg mL -1] against Vibrio spp. (UP>CP>PAP). UP propolis significantly inhibited the growth of Vibrio cholerae O1 serotype Inaba (MIC 50<50 μg mL-1), V. cholerae non-O1 (MIC 50<50 μg mL-1), V. vulnificus (MIC 50<50 μg mL-1), and V. cholerae O1 serotype Ogawa (MIC50 100 μg mL-1), in a concentration-dependent manner. The UP propolis constituents, galangin and caffeic acid phenethyl ester (CAPE), exhibited a potent growth inhibitory activity (MIC50 0.05-0.1 mmol l-1) against V. cholerae strains (non-O1 and serotype Ogawa). The strong anti-Vibrio activity of Sonoran propolis and some of its chemical constituents (galangin and CAPE) support further studies on the clinical applications of this natural bee product against different Vibrio spp., mainly V. cholerae.

Idioma originalInglés
Páginas (desde-hasta)150-158
Número de páginas9
PublicaciónFoodborne Pathogens and Disease
Volumen10
N.º2
DOI
EstadoPublicada - 1 feb. 2013

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