TY - JOUR
T1 - Antiviral effects of Brazilian green and red propolis extracts on Enterovirus surrogates
AU - Silva-Beltrán, Norma Patricia
AU - Balderrama-Carmona, Ana Paola
AU - Umsza-Guez, Marcelo Andrés
AU - Souza Machado, Bruna Aparecida
N1 - Publisher Copyright:
© 2019, Springer-Verlag GmbH Germany, part of Springer Nature.
PY - 2019/12/19
Y1 - 2019/12/19
N2 - Propolis is a natural product of bees with biological activities that are mainly associated with bee type and geographic origin. Propolis extract has been proposed with several applications in environmental health. The ethanol extracts have shown good antimicrobial activity. The association of this technique with ultrasound-assisted extraction has been studied to improve the characteristics of the obtained extracts. Thus, the objective of this work is to verify the antiviral action against two strains of bacteriophages of two extracts of Brazilian propolis (green and red) obtained by conventional extraction and ultrasonic extraction. The activities of the propolis red and green extracts were confirmed by the significant ~3 and ~4.5 Log 10 PFU/mL reduction in the concentrations of the MS2 and Av-08 bacteriophages, respectively. It was found that ultrasound-assisted extraction is comparable to the maceration process and demonstrated the best antiviral activities. Brazilian red propolis was more effective than green propolis in viral reduction in all treatments.
AB - Propolis is a natural product of bees with biological activities that are mainly associated with bee type and geographic origin. Propolis extract has been proposed with several applications in environmental health. The ethanol extracts have shown good antimicrobial activity. The association of this technique with ultrasound-assisted extraction has been studied to improve the characteristics of the obtained extracts. Thus, the objective of this work is to verify the antiviral action against two strains of bacteriophages of two extracts of Brazilian propolis (green and red) obtained by conventional extraction and ultrasonic extraction. The activities of the propolis red and green extracts were confirmed by the significant ~3 and ~4.5 Log 10 PFU/mL reduction in the concentrations of the MS2 and Av-08 bacteriophages, respectively. It was found that ultrasound-assisted extraction is comparable to the maceration process and demonstrated the best antiviral activities. Brazilian red propolis was more effective than green propolis in viral reduction in all treatments.
KW - Assisted ultrasound
KW - Bacteriophages
KW - Propolis extracts
UR - http://www.scopus.com/inward/record.url?scp=85077157227&partnerID=8YFLogxK
U2 - 10.1007/s11356-019-07458-z
DO - 10.1007/s11356-019-07458-z
M3 - Artículo
C2 - 31889278
AN - SCOPUS:85077157227
SN - 0944-1344
VL - 27
SP - 28510
EP - 28517
JO - Environmental Science and Pollution Research
JF - Environmental Science and Pollution Research
IS - 23
ER -