TY - JOUR
T1 - Biosynthesis of zinc oxide nanoparticles using Tamarix chinensis extract
T2 - evaluation of antioxidant, antimicrobial, and anti-MCF-7 cancer activities
AU - Bouttier-Figueroa, Diego Carlos
AU - Loreto-Romero, Manuel Alfredo
AU - González-Gutiérrez, Francisco Humberto
AU - Cortez-Valadez, Manuel
AU - Flores-Acosta, Mario
AU - Meneses-Sagrero, Salvador Enrique
AU - Robles-Zepeda, Ramón Enrique
N1 - Publisher Copyright:
© 2024 Taylor & Francis Group, LLC.
PY - 2025
Y1 - 2025
N2 - This study explores the green synthesis of zinc oxide nanoparticles (ZnONPs) using Tamarix chinensis extract, known for its hepatoprotective and anti-inflammatory phytochemicals. The ZnONPs were synthesized using ZnSO4 and NaOH, resulting in an average size of 125 nm, as confirmed by scanning electron microscopy (SEM). X-ray diffraction (XRD) analysis revealed a hexagonal crystalline structure. UV-Vis spectroscopy showed an absorption peak at 360 nm, corresponding to a bandgap of 3.37 eV, making these nanoparticles suitable for controlled drug delivery systems. The antioxidant activity of T. chinensis extract was evaluated using the DPPH assay, demonstrating an 80% inhibition of free radicals at 500 µg/mL, surpassing the antioxidant potential of the ZnONPs. The antimicrobial efficacy of the ZnONPs was evidenced by a minimum inhibitory concentration (MIC) of <50 µg/mL against Escherichia coli and Staphylococcus aureus. Additionally, the ZnONPs exhibited antiproliferative activity with an IC50 of 20.80 µg/mL in MCF-7 breast cancer cells, highlighting their potential for biomedical applications. These findings suggest the promising multifunctional role of biosynthesized ZnONPs in healthcare and technological innovations.
AB - This study explores the green synthesis of zinc oxide nanoparticles (ZnONPs) using Tamarix chinensis extract, known for its hepatoprotective and anti-inflammatory phytochemicals. The ZnONPs were synthesized using ZnSO4 and NaOH, resulting in an average size of 125 nm, as confirmed by scanning electron microscopy (SEM). X-ray diffraction (XRD) analysis revealed a hexagonal crystalline structure. UV-Vis spectroscopy showed an absorption peak at 360 nm, corresponding to a bandgap of 3.37 eV, making these nanoparticles suitable for controlled drug delivery systems. The antioxidant activity of T. chinensis extract was evaluated using the DPPH assay, demonstrating an 80% inhibition of free radicals at 500 µg/mL, surpassing the antioxidant potential of the ZnONPs. The antimicrobial efficacy of the ZnONPs was evidenced by a minimum inhibitory concentration (MIC) of <50 µg/mL against Escherichia coli and Staphylococcus aureus. Additionally, the ZnONPs exhibited antiproliferative activity with an IC50 of 20.80 µg/mL in MCF-7 breast cancer cells, highlighting their potential for biomedical applications. These findings suggest the promising multifunctional role of biosynthesized ZnONPs in healthcare and technological innovations.
KW - Green synthesis
KW - plant extract
KW - zinc oxide nanoparticles
UR - http://www.scopus.com/inward/record.url?scp=85214230841&partnerID=8YFLogxK
U2 - 10.1080/10826068.2024.2446461
DO - 10.1080/10826068.2024.2446461
M3 - Artículo
AN - SCOPUS:85214230841
SN - 1082-6068
JO - Preparative Biochemistry and Biotechnology
JF - Preparative Biochemistry and Biotechnology
ER -