TY - JOUR
T1 - Characterization of OSA starch-based films with nut-byproducts extracts for potential application as natural wound dressing
AU - Leon-Bejarano, Marcos
AU - Santos-Sauceda, Irela
AU - Dórame-Miranda, Ramón Francisco
AU - Medina-Juárez, Luis Ángel
AU - Gámez-Meza, Nohemí
AU - García-Galaz, Alfonso
AU - Simsek, Senay
AU - Ovando-Martínez, Maribel
N1 - Publisher Copyright:
© 2023, The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.
PY - 2023/12
Y1 - 2023/12
N2 - OSA-starch based bioactive films with pecan nutshell or hazelnut skin extracts were prepared, characterized, and evaluate. The hemocompatibility assay showed that bioactive films with extracts are slightly hemolytic. Bioactive films with 0.25% and 0.50% (w/v) of extracts showed antibacterial activity against S. aureus, S. epidermidis and K. pneumoniae. Due to the hemocompatibility and microbial assays, only films with 0.25% and 0.50% of each extract were characterized. Bioactive films depicted a homogeneous surface and compact structure, due to plasticization and molecular interactions through hydrogen linkages between extracts and modified starch network, confirmed by Fourier-transform infrared spectroscopy (FTIR). The water uptake capacity (~ 100% after 24 h), water vapor transmission rate (WVTR) (2300–2600 g/m2·day) and contact angle values (92–100°) confirmed bioactive films have moderate water properties. Finally, mechanical properties of bioactive films showed an elastic behavior with young´s modulus values lower than 25 MPa and elongation percentages around 290%, indicating a plasticizing effect of the extracts. Overall results suggest elaborated bioactive films could have potential application as wound dressings. Graphical abstract: [Figure not available: see fulltext.].
AB - OSA-starch based bioactive films with pecan nutshell or hazelnut skin extracts were prepared, characterized, and evaluate. The hemocompatibility assay showed that bioactive films with extracts are slightly hemolytic. Bioactive films with 0.25% and 0.50% (w/v) of extracts showed antibacterial activity against S. aureus, S. epidermidis and K. pneumoniae. Due to the hemocompatibility and microbial assays, only films with 0.25% and 0.50% of each extract were characterized. Bioactive films depicted a homogeneous surface and compact structure, due to plasticization and molecular interactions through hydrogen linkages between extracts and modified starch network, confirmed by Fourier-transform infrared spectroscopy (FTIR). The water uptake capacity (~ 100% after 24 h), water vapor transmission rate (WVTR) (2300–2600 g/m2·day) and contact angle values (92–100°) confirmed bioactive films have moderate water properties. Finally, mechanical properties of bioactive films showed an elastic behavior with young´s modulus values lower than 25 MPa and elongation percentages around 290%, indicating a plasticizing effect of the extracts. Overall results suggest elaborated bioactive films could have potential application as wound dressings. Graphical abstract: [Figure not available: see fulltext.].
KW - Biomaterial
KW - Hazelnut skin
KW - Modified starch
KW - Pecan nutshell
KW - Wound dressings
UR - http://www.scopus.com/inward/record.url?scp=85147282547&partnerID=8YFLogxK
U2 - 10.1007/s00289-023-04707-7
DO - 10.1007/s00289-023-04707-7
M3 - Artículo
AN - SCOPUS:85147282547
SN - 0170-0839
VL - 80
SP - 13199
EP - 13215
JO - Polymer Bulletin
JF - Polymer Bulletin
IS - 12
ER -