Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico: PREVISY

Alejandro Arturo Castro-Juarez, Araceli Serna-Gutiérrez, Heliodoro Alemán-Mateo, Ana Cristina Gallegos-Aguilar, Norma Alicia Dórame-López, Abraham Valenzuela-Sánchez, Diana Marcela Valenzuela-Guzmán, Rolando Giovanni Díaz-Zavala, Rene Urquidez-Romero, Julián Esparza-Romero*

*Autor correspondiente de este trabajo

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

1 Cita (Scopus)

Resumen

To evaluate the effectiveness of the healthy lifestyle promotion program for Yaquis (PREVISY) on insulin resistance in the short- and medium-term periods in adults who are overweight/obese and have an increased risk for diabetes. Using a translational research design, an intervention program was implemented in a sample of 93 Yaqui adult subjects. The effectiveness of PREVISY was evaluated by comparing the levels of Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) and the Triglycerides-Glucose Index (TyG index) at 6 and 12 months using a paired t-test. Results: In the subjects who completed the program, a decrease in the HOMA-IR index (∆ = −0.91 and ∆ = −1.29, p ≤ 0.05) and the TyG index (∆ = −0.24 y ∆ = −0.20, p ≤ 0.05) was observed in the short- and medium-term period, respectively. Subjects with body weight loss ≥ 10% showed decreased levels of HOMA-IR (∆ = −3.32 and ∆ = −4.89, p ≤ 0.05) and the TyG index (∆ = −0.80 and ∆ = −0.60, p ≤ 0.05) at 6 and 12 months, respectively. A stronger benefit of the program was found in subjects with obesity (vs. overweight) and with high and very high risk of diabetes (vs. moderate risk) in IR markers (p ≤ 0.05). The PREVISY program demonstrated its effectiveness in the improvement of some markers of insulin resistance in Yaqui adults at risk of diabetes.

Idioma originalInglés
Número de artículo597
PublicaciónNutrients
Volumen15
N.º3
DOI
EstadoPublicada - feb. 2023

Nota bibliográfica

Publisher Copyright:
© 2023 by the authors.

Huella

Profundice en los temas de investigación de 'Effectiveness of a Lifestyle Change Program on Insulin Resistance in Yaquis Indigenous Populations in Sonora, Mexico: PREVISY'. En conjunto forman una huella única.

Citar esto