Oxidative potential of metal-polluted urban dust as a potential environmental stressor for chronic diseases

Benedetto Schiavo*, Diana Meza-Figueroa, Efrain Vizuete-Jaramillo, Agustin Robles-Morua, Aracely Angulo-Molina, Pablo A. Reyes-Castro, Claudio Inguaggiato, Belem Gonzalez-Grijalva, Martin Pedroza-Montero

*Autor correspondiente de este trabajo

Resultado de la investigación: Contribución a una revistaArtículorevisión exhaustiva

Resumen

Oxidative stress (OS) associated with metals in urban dust has become a public health concern. Chronic diseases linked to general inflammation are particularly affected by OS. This research analyzes the spatial distribution of metals associated with OS, the urban dust´s oxidative potential (OP), and the occurrence of diseases whose treatments are affected by OS. We collected 70 urban dust samples during pre- and post-monsoon seasons to achieve this. We analyzed particle size distribution and morphology by scanning electron microscopy, as well as metal(loid)s by portable X-ray fluorescence, and OP of dust in artificial lysosomal fluid by using an ascorbic acid depletion assay. Our results show that the mean concentration of Fe, Pb, As, Cr, Cu, and V in pre-monsoon was 83,984.6, 98.4, 23.5, 165.8, 301.3, and 141.9 mg kg−1, while during post-monsoon was 50,638.8, 73.9, 16.7, 124.3, 178.9, and 133.5 mg kg−1, respectively. Impoverished areas with the highest presence of cardiovascular, cancer, diabetes, and respiratory diseases coincide with contaminated areas where young adults live. We identified significant differences in the OP between seasons. OP increases during the pre-monsoon (from 7.8 to 237.5 nmol AA min−1) compared to the post-monsoon season (from 1.6 to 163.2 nmol AA min−1). OP values are much higher than measured standards corresponding to contaminated soil and urban particulate matter, which means that additional sources beside metals cause the elevated OP. The results show no risk from chronic exposure to metals; however, our results highlight the importance of studying dust as an environmental factor that may potentially increase oxidative stress.

Idioma originalInglés
PublicaciónEnvironmental Geochemistry and Health
DOI
EstadoAceptada/en prensa - 2022
Publicado de forma externa

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Publisher Copyright:
© 2022, The Author(s), under exclusive licence to Springer Nature B.V.

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