Retino-protective effect of Bucida buceras against oxidative stress induced by H2O2 in human retinal pigment epithelial cells line

Reactive Oxygen Species (ROS) impair the physiological
functions of Retinal Pigment Epithelial (RPE) cells, which are known as
one major cause of age-related macular degeneration and retinopathy diseases. The purpose of this study is to explore the cytoprotective effects
of the antioxidant Bucida buceras extract in co-treatment with hydrogen
peroxide (H2O2) delivery as a single addition or with continuous generation
using glucose oxidase (GOx) in ARPE-19 cell cultures. The mechanism
of Bucida buceras extract is believed to be associated with their
antioxidant capacity to protect cells against oxidative stress.