Thiourea-Based Receptors for Anion Recognition and Signaling

Jancarlo Gomez-Vega, Adrian Vasquez-Cornejo, Octavio Juárez-Sánchez, David O. Corona-Martínez, Adrián Ochoa-Terán, Karla A. López-Gastelum, Rogerio R. Sotelo-Mundo, Hisila Santacruz-Ortega, Juan Carlos Gálvez-Ruiz, Refugio Pérez-González, Karen Ochoa Lara*

*Autor correspondiente de este trabajo

Producción científica: Contribución a una revistaArtículorevisión exhaustiva

Resumen

This work reports on two thiourea-based receptors with pyridine and amine units including 1-naphthyl (MT1N) and 4-nytrophenyl (MT4N) as signaling units. For both compounds, their affinity and signaling ability toward various anions of different geometry and basicity in DMSO were studied using UV-vis, fluorescence, and 1H NMR techniques. Anion recognition studies revealed that both MT1N and MT4N have, in general, high affinities toward basic anions. In this regard, a higher acidity of the MT4N receptor was demonstrated. Furthermore, MT4N has a higher affinity for fluoride (log K1 = 5.98) than for the other anions and can effectively detect it through colorimetric changes that can be monitored by the UV-vis technique. The interaction between receptors and anions mainly involves the hydrogens of the amino and thiourea groups of the former. Complementary single-crystal X-ray diffraction studies and molecular modeling at the DFT level were also performed.

Idioma originalInglés
Páginas (desde-hasta)4412-4422
Número de páginas11
PublicaciónACS Omega
Volumen9
N.º4
DOI
EstadoPublicada - 30 ene. 2024

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© 2024 The Authors. Published by American Chemical Society.

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